Hi pinotgraves and welcome here! Yes, the 16GB SDHC should work fine with GRDII. But if you are a RAW shooter, get only the fast one (Class 6) and from brands like Panasonic or Sandisk.
But If I may suggest you something, get couple of 4GB cards instead one 16GB. Higher capacity cards used to be a bit slower during the writing process. Don't ask me why
In addition, with 4GB card there is much lower risk of loosing some important photos because you are forced to empty the card much more frequently. I personally use 4GB Panasonic Class6 and I'm perfectly happy with it.